Distinguish between acute, sub-acute and chronic toxicity tests. What other types of toxicity tests may be used to identify toxicological hazards?

Short Answer Questions

Word limit per question: 150 words ±10%.

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Answer each of the following questions. The purpose of these questions is to encourage you to engage with the material presented in modules 1 – 5.

If you have completed the readings recommended for each module you should be able to answer these questions. Answers do not need to be in an essay format. You are expected to reference all cited literature excluding the published teaching materials on Blackboard.

Question 1: Distinguish between acute, sub-acute and chronic toxicity tests. What other types of toxicity tests may be used to identify toxicological hazards?

Question 2: Indicate the difference between exposure route and exposure pathway. Explain why the effects of a hazard may vary between acute and chronic exposure?

Question 3: Describe common ways of characterizing the dose – response relationship. Outline the difference between the threshold and non-threshold approaches.

Question 4: Define risk characterization and the methods to characterize risks. List the uncertainties associated with this process.

Question 5: Define exposure and describe six (6) important elements to consider during environmental exposure assessment.