How are differentiated T- and B-cells targeted to sites of infection in peripheral mucosal and skin tissues (this Week)?

CD4+ T-helper subsets

1. How are specific CD4+ T-helper subsets generated (see Week 6)?

2. How are differentiated T- and B-cells targeted to sites of infection in
peripheral mucosal and skin tissues (this Week)?

3. How does the gut maintain immune tolerance in the presence of huge
numbers of commensal bacteria?