Risk of reducing pilot number on long haul flight (human factor)

1/ How are human factors affected when reducing the number of pilots on long-haul flights (more than 9h30) from 4 or 3 to only 2? What are the Risks? (example and reference from books)
Definition of human factors to be used for this work: lack of communication, lack of teamwork, lack of assertiveness, complacency, fatigue, stress, lack of knowledge, lack of resources, lack of awareness, distraction, pressure and norms.

  • One website to help understand the subject in the aviation industry: https://www.aeroimpulse.de/en/insights/human-factors-definition/

2/ Can we make a parallel with other industries such as train or other? and how did it affect them?

3/ What solution can we find to maintain a similar or higher level of safety on long-haul flights operated with only 2 pilots in the future? (Creative solutions are welcomed as well as solutions from other industries)