Your colleague has designed the bioreactor shown in the drawing below. You are in charge of cleaning validation. What design features might cause problems with successfully cleaning this piece of equipment?

Bioreactor

Your colleague has designed the bioreactor shown in the drawing below. You are in charge of cleaning validation. What design features might cause problems with successfully cleaning this piece of equipment?

Note that the lines are not to scale.

Name at least five items for full credit and explain what the problem would be.