Read the case studies below (endocrine or musculoskeletal), choose one case study to and discuss the pathophysiology of the condition.

Case Study 1
Sharon Munroe, 26 year old caucasian female, has a history of Polycystic Ovarian Syndrome (PCOS) for the past 6 years. Medical history includes, cessation of menses several years ago, 20 kg weight gain over the past 5 years, increasing hirsuitism, acne and 2 previous miscarriages and infertility.