Identify the initial rationale that prompted the study and then the major change that occurred. Define the significance of this study: Compare the perceived benefit at the time versus the risks. Define at least five protections instituted that would ensure this would not be repeated today?

Tuskegee Study of Untreated Syphilis in the Negro Male

1. A) Identify the initial rationale that prompted the study and then the major change that occurred;
   1. Describe the two profound ethical dilemmas within the

2. A) Define the significance of this study: Compare the perceived benefit at the time versus the risks;
   1. Describe the key positive and the key negative legacies of

3. A) Define each of the following ethical principles as it relates to research and medicine
   1. Provide example(s) of the ethical breach(es) for each principle in the study
   2. Compare/explain current advances in research; and where applicable, in patient care

• Informed consent
• Autonomy
• Beneficence / Nonmaleficence
• Veracity
• Confidentiality
• Justice
• Utility
• Paternalism

4. Define at least five protections instituted that would ensure this would not be repeated today?
5. Mechanics and grammar Paper guidelines:

Title page with name

Calibri 12-point font, double-spaced Include page numbers – 5-page limit

Cite sources – Use AMA style for referencing and bibliography – do not use APA format