Introduce the function of the Lac operon regulatory network. Describe the experimental methods used by Phillips et al. to obtain the data in Figure 2 Discuss the deterministic model used by Phillips et al.

Directions

Main source for this paper should be from the The Sources mentioned below

Phillips et al. and 2. Setty el al. The content and goal listed below must be addressed.

Writing doesn’t have to follow traditional essay writing style need to be Content Focused

Background reading if need on lac operon regulation (optional)

Book in pdf (easier to read if downloaded):

Table of contents/index to find topics faster

Do control and F for find feature to search topics

Outside reading/ sources not necessary.

Essay must not focus on the writing style but must focus on Content.

Paper Topic: Diversity in Lac operon regulation among Escherichia coli isolates

Essay : Diversity in Lac operon regulation among Escherichia coli isolates.

Google unfamiliar terms to gain understanding of the paper

Title: Diversity in Lac operon regulation among Escherichia coli isolates.

Sources:

Phillips KN, Widmann S, Lai H-Y, Nguyen J, Ray JCJ, Balázsi G, Cooper TF. 2019. Diversity in lac operon regulation among diverse Escherichia coli isolates depends on the broader genetic background but is not explained by genetic relatedness. mBio10:e02232-19. https://doi.org/10.1128/mBio.02232-19.
Setty et al. Detailed map of a cis regulatory function. PNAS 2003.

Goal: Describe the concepts leading to the surface plots shown in Figure 2 and supplemental Fig S2.

Contents MUST include these points below:

Introduce the function of the Lac operon regulatory network.
Describe the experimental methods used by Phillips et al. to obtain the data in Figure 2
Discuss the deterministic model used by Phillips et al. (supplemental Text1)