Picot Questions
Sample Questions:
Intervention: In African–American female adolescents with hepatitis B (P), how does acetaminophen (I) compared to ibuprofen (C) affect liver function (O)?
Etiology: The question could read: Are 30– to 50–year–old women (P) who have high blood pressure (I) compared with those without high blood pressure (C) at increased risk for an acute myocardial infarction (O) during the first year after hysterectomy (T)?
Diagnosis: In middle–aged males with suspected myocardial infarction (P), are serial 12–lead ECGs (I) compared to one initial 12–lead ECG (C) more accurate in diagnosing an acute myocardial infarction (O)?
Prognosis/Prediction: 1) For patients 65 years and older (P), how does the use of an influenza vaccine (I) compared to not received the vaccine (C) influence the risk of developing pneumonia (O) during flu season (T)?
2) In patients who have experienced an acute myocardial infarction (P), how does being a smoker (I) compared to a non–smoker (C) influence death and infarction rates (O) during the first 5 years after the myocardial infarction (T)?
Meaning: How do 20–something males (P) with a diagnosis of below the waist paralysis (I) perceive their interactions with their romantic significant others (O) during the first year after their diagnosis (T)?