COVID-19 Testing

During the COVID-19 pandemic, testing is relied upon heavily to help develop prevention and control measures. The validity of tests used can impact individual and community decisions and ultimately COVID-19 related morbidity and mortality.

Instructions
For this assignment, see “Serology-based tests for COVID-19” (Links to an external site.) from the Johns Hopkins Center for Health Security. This article discusses the sensitivity and specificity of serology-based tests for COVID-19.

From the Johns Hopkins list of serology-based tests, select two different types of serology assays from two different manufacturers and answer the following questions:

Describe, compare, and contrast each test including a discussion on sensitivity and specificity. Is one test better than the other?
Discuss how these tests might be available to the community. For example, are they easily accessible and inexpensive?
When screening large groups for COVID-19, would you select a less valid test in exchange for ease of use, patient comfort, or cost? Meaning, if the specific test was cheaper or easier to use, would you choose this type of test even if it meant compromising test validity?
What are the consequences of a false positive COVID-19 test?
What are the consequences of a false negative COVID-19 test?
Review the following article for additional information on the impact of COVID-19 test validity.

West, C.P., Montori, V.M., & Sampathkumar, P. (2020). COVID-19 testing: The threat of false-negative results (Links to an external site.). Mayo Clin Proceedings, 95(6), 1127–1129.