Critically appraise 2 stages from drug discovery and 2 form drug development with reference to drugs discovered and developed for nervous system disorders preferably Epilepsy and Alzheimer’s. different drugs should be analysed throughout, appraising the success rate. ethics. cost-effectiveness, what worked and what didn’t in terms of chosen drug.

Stages of drug discovery and drug development disorders of the nervous system.

Drug discovery stages:

• 1)Target identification and validation
• 2) Hit discovery
• 3) lead identification

Drug development stages:

• 1) Lead optimization (in vivo)
• 2) Human clinical trials
• 3) regulatory body approval.

Can critically appraise 2 stages from drug discovery and 2 form drug development with reference to drugs discovered and developed for nervous system disorders preferably Epilepsy and Alzheimer’s. different drugs should be analysed throughout, appraising the success rate. ethics. cost-effectiveness, what worked and what didn’t in terms of chosen drug. preferably up-to-date references