Write a research of GSD glycogen storage disorder using 5 peer-reviewed journal articles or textbooks.

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Disorders of Glycogen and Fatty Acid Metabolism

Write a research of GSD glycogen storage disorder using 5 peer-reviewed journal articles or textbooks. There should be 10 citations all in AMA format.

Use the suggested outline:

  • Pathologic Features/Genetic Basis of Disease
  • Laboratory Features
  • Differential Diagnosis
  • Management/ Treatment
  • Complications
  • Prognosis
  • Current/ Future Research (Including Clinical Trials)

 

What happens when our blood pressure increases? What happens when the blood pressure decreases? What happens when there is too much water? What happens when there is not enough water?

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Negative feedback mechanism

Assignment- Homeostasis

Read about  Homeostasis, specifically “Negative Feedback Mechanism.” You may use/Google other sources and watch videos if you need more explanation.

Your assignment is to give two (2) specific examples of a negative feedback mechanism, but summarize it in… short phrases listed in a bulleted(numbered format), from the 1) stimulus to 2) sensors to 3) control center to 4) effectors and 5) the result/effect.

What happens when our blood pressure increases? What happens when the blood pressure decreases? What happens when there is too much water (water intoxication)?

What happens when there is not enough water (dehydration)?

What happens when there is too much or too little calcium? sodium? thyroid hormones? potassium? Carbon dioxide? Low pH? High pH?

What happens when the body gets really cold?

There are a lot, because there are changes we subject/expose the body to everyday, and our physiology  fixes it everyday.

 

Based on these results, are the genes linked or not? How would the phenotypic frequencies look if the genes were not linked? Which two numbered phenotypes in Table 1, represent offspring of the parental types?

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BIO340 Activity #4: 3–Point Cross, Gene Order and Mapping

I. Determining single–crossovers (SCOs), double–crossovers (DCOs) and gene order.

(Initially, you do not know what the order of the genes is on the chromosome. Your DCOs will be compared to your parental types to determine which gene is in the middle.)
We want to map the distance between genes for: leaf color (A – green, dominant; a – yellow, recessive), leaf texture (B – rough, dominant; b – smooth, recessive), and plant fertility (F – normal, dominant; f – variable, recessive).

Your mapping cross is like a test cross. One parent (mapping individual) is heterozygous for all genes (so crossover events can be assessed) while the other parent (“cryptic” or “tester”) is
homozygous recessive for all genes (so crossover events will be cryptic, i.e. undetectable).

Gene order is not yet determined.

Below, (in the order in which the genes are presented above) write the genotypes of the mapping cross individual (i.e. the heterozygote) and the cryptic individual: _ X ___ (mapping) (cryptic)

Table 1: Progeny from Mapping Cross
Phenotype Frequency Phenotype Frequency
1. Green, rough, normal 95 5. Green, smooth, normal 900
2. Yellow, rough, normal 50 6. Yellow, smooth, normal 5
3. Green, rough, variable 5 7. Green, smooth, variable 50
4. Yellow, rough, variable 900 8. Yellow, smooth, variable 95

Based on these results, are the genes linked or not?
How would the phenotypic frequencies look if the genes were not linked?
Which two numbered phenotypes in Table 1, represent offspring of the parental types?
Using slash notation, the parental type offspring have genotypes: __ and ___.
The actual chromosomal configuration of the mapping individual in the cross must have been___ /__.

Which two numbered phenotypes in Table 1, represent offspring from DCOs?

Using slash notation, the DCO offspring have genotypes: __ and __.
Comparing the mapping individual’s chromosome configuration with the chromosome configuration of the DCOs, you can tell which gene is in the center of the other two based upon which gene “switched sides” from parental type chromosomes to DCO type chromosomes? Which gene is in the middle?  The gene order then is:

II. Map Distance
To figure out the distances, we must identify SCOs between the gene in the middle and each of the other two genes.
Looking at the chromosomes inherited by each progeny type above in Table 1, identify the
numbered offspring types that result from a single–crossover between the gene on the far left (as you drew them above) and the middle gene:
The map distance between these genes = ([(the number of SCOs between these genes) + (the number of DCOs)] / (Total number of offspring) X 100.
Calculate the map distance between the gene on the far left and the middle gene:
Complete the figure illustrating the products of a double–crossover (in meiosis)
Mapping Individual Double–Crossover DCO Products

Looking at the chromosomes inherited by each progeny type above in Table 1, identify the numbered offspring types that result from a single–crossover between the middle gene and the gene on the far right (as you drew them above):

Again, the map distance between these genes = ([(the number of SCOs between these genes) + (the number of DCOs)] / (Total number of offspring) X 100.
Calculate the map distance between the middle gene and the gene on the far right:

 

Why did you choose this disease? Why do you think is an important disease we should all know more about? What is the microbe that causes this disease and what have you already learned about it?

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Tuberculosis

In a document of at least 300 words address the following:

Why did you choose this disease?
Why do you think is an important disease we should all know more about?
What is the microbe that causes this disease and what have you already learned about it? (briefly!)
What are two significant questions you hope to answer in researching this disease?
Provide at least 2 APA style references from reliable objective sources on your topic.
You will want to consult our earlier timeline and WHO document on Infectious Diseases as well as our course library guide in completing this work.

Describe your undergraduate summer, clinical, industrial research and/or any teaching experiences and indicate how these experiences sparked your passion for research? How will obtaining a graduate degree in the biomedical sciences help you achieve your long-term career goals?

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Bachelor in Biotechnology

Essay Question 1

Describe your undergraduate summer, clinical, industrial research and/or any teaching experiences and indicate how these experiences sparked your passion for research? How will obtaining a graduate degree in the biomedical sciences help you achieve your long-term career goals?

Essay Question 2

Describe what you are passionate about and how this has led to an interest in our graduate program. Identify up to 3 of our faculty members in whose research you are particularly interested, and briefly tell us why

Applying PhD at Biomedical science in UT Health San Antonio

https://www.uthscsa.edu/academics/biomedical-sciences/programs

 Little background if useful:

Now 4th year of college at major biotechnology

Bachelor in Biotechnology 2023

Research involved in:

  • Effect of intranasal oxytocin on the expression of 5-hydroxytryptamine in hippocampus of rats with post-traumatic stress disorder
  • Molecular mechanism of hypoxia affecting collagen expression and hydroxylation modification in scleral fibroblasts
  • Evaluation of the depression states of rats during establishing experimental model and recovery

Describe how the external layers of bacteria differ if they are Gram-negative or Gram-positive or if the bacterium lives in different environments.

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BIO 205 Prokaryote Diagram

The purpose of this assignment is to get you used to taking the detailed information that you learn in the lecture and compiling it to see the big picture. Throughout the semester, you should get used to drawing diagrams in your notes to help you break down and understand concepts.

After completing this assignment, you should be able to describe how the external layers of bacteria differ if they are Gram-negative or Gram-positive or if the bacterium lives in different environments. You are only responsible for drawing one organism, but make sure you can explain how the other organisms would be different.

Instructions:

First letter of last name Type of organism
A-G Gram (+) bacterium living in a suitable environment
H-L Gram (+) bacterium living in a hostile environment
M-S Gram (-) bacterium living in a suitable environment
T-Z Gram (-) bacterium living in a hostile environment

 

In the table above, I have assigned a type of prokaryote to each person, depending on your last name.  Hand-draw a diagram of the organism that you have been assigned. Include the internal and external features that are listed below, as long as the feature applies to your assigned organism.

Clearly label each structure that you draw and provide a brief description of the macromolecules that it is made of (i.e. phospholipid bilayer and proteins, lipopolysaccharides, etc.). You may choose to include color in your diagram, but every structure that you draw must be labeled.

 

External layers (not in order)

  • Outer membrane
  • Cytoplasmic membrane
  • Glycocalyx
  • Cell wall
  • S layer

Internal structures

  • Chromosome
  • Plasmid
  • Inclusion bodies
  • Ribosomes
  • Cytoplasm
  • Cytoskeleton

 

Submission instructions:

  1. Take a picture of your diagram (a cell phone image is fine).
  2. Paste the picture into a new Word document
  3. Type your full name and the organism you were assigned at the top of the document
  4. Save the document as a PDF. (File à save as à select PDF as the “save as type”)
  5. Submit your PDF to the Blackboard assignment

Note: since you will be submitting this electronically, you may type the descriptions of each structure in the word document, if there is not enough room to put it of your diagram. If you do this, your hand-drawn diagram still needs to have labels naming every structure that you draw.

Discuss any aspect of healthcare ethics from the Hippocratic Oath, or ethical statement of a discipline, to ethical decision making processes.

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Ethics in healthcare

This paper can discuss any aspect of healthcare ethics from the Hippocratic Oath, or ethical statement of a discipline, to ethical decision making processes. You must reference or cite at least two sources.

You must submit the paper thru blackboard. Papers submitted after the due date will have 10 points deducted from the total score. Written Paper 500 words

 

How does a cell illustrate the basic concepts of life? How does rough endoplasmic reticulum differ from smooth endoplasmic reticulum? If a cell’s lysosomes do not function property, what would be the outcome?

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BIOL 108 WORKSHEET 2

Copy and paste the following worksheet into a new document, then answer the following questions. Submit it to the Dropbox by Sunday at 11:59 pm Central time. Any information copied from any source INCLUDING THE TEXT must include quotation marks and a reference. Put your answers in bold and include the question number with your answer. All questions worth 1 point unless otherwise stated.

1. How does a cell illustrate the basic concepts of life? Be specific and use at least 3 characteristics of life.

2. How does rough endoplasmic reticulum differ from smooth endoplasmic reticulum?

3. If a cell’s lysosomes do not function property, what would be the outcome?

4. What is the main difference between prokaryotic and eukaryotic cells?

5. Identify three components of the cytoskeleton.

6. Explain the fluid-mosaic model of the plasma membrane.

7. In what specific way is osmosis different than diffusion?

8. What happens to red blood cells when they are placed in a hypertonic solution?

9. How does active transport differ from facilitated transport?

10. Identify and describe 4 ways that substances leave or enter cells. (2 pts)

11. For each process, indicate where it occurs in the cell and whether oxygen is required: glycolysis, citric acid cycle, and electron transport (2 pts)

12. What is the function of the Golgi apparatus?

13. Identify the 4 main tissue types in the body.

14. How do compact and spongy bone differ?

15. Smooth muscle and cardiac muscle are under involuntary control. How does this help the body maintain homeostasis?

16. What type of cells line the digestive tract? Be specific.

17. Identify the -formed elements” of blood.

18. What are dendritic cells?

19. How is the skin involved in the production of vitamin Din humans?

20. Which organs/structures are found in the thoracic cavity?

21. The pancreas is part of which two body systems?

22. Explain how negative feedback helps the body maintain homeostasis.

23. If a person lacks melanocytes, what would be the outcome?

Explain why this would be correct. An important cellular structure is the cell (plasma) membrane. Identify and explain a specific function of the cell membrane that you feel is the most important in achieving homeostasis.

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D3b

Consider cell structure and functions, and the organization and function of the human body. When viewed together, this implies the functions of the human body are dependent upon cellular activity. Explain why this would be correct. An important cellular structure is the cell (plasma) membrane. Identify and explain a specific function of the cell membrane that you feel is the most important in achieving homeostasis.

Identify one function of the integumentary system you feel is the most important and why. Hypothesize that the function you identified ceased to function – how would homeostasis be impacted?

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D4B

Consider the integumentary system in detail. Explain the structures of this system that qualifies it to be termed a system. Identify one function of the integumentary system you feel is the most important and why. Hypothesize that the function you identified ceased to function – how would homeostasis be impacted?