Write an essay explaining the postulates of the cell theory.

Postulates of the cell theory

Write an essay explaining the postulates of the cell theory.

What are the functions of the CV system? Between the visceral and parietal layers of the pericardium is a potential space called the _________ cavity; it is filled with ________ fluid, which reduces friction.

Chapter 13:  Cardiovascular System

 

Cardiovascular System:

The cardiovascular (CV) system consists of the heart, and blood vessels (arteries, capillaries and veins).

What are the functions of the CV system?  ___________________________________________________

Structure of the Heart:

The heart is a hollow, ___________-shaped, muscular pump within the _________; it rests on the _________.

The average adult heart is ___________ cm long and ___________ cm wide.

The heart lies posterior to the sternum; its apex extends to the _________ intercostal space.

 

Pericardium:

The pericardium consists of two layers: the outer, tough connective tissue _________ pericardium, surrounding a more delicate double-layered sac that surrounds the heart.

 

The inner layer directly covers the heart and is called the _________ pericardium, or _________.

 

At the base of the heart, the inner layer folds back to become the __________ pericardium.

Between the visceral and parietal layers of the pericardium is a potential space called the _________ cavity; it is  filled with ________ fluid, which reduces friction.

 

Wall of the Heart:

The wall of the heart is composed of three distinct layers.  The outermost layer, the __________, is made up of

connective tissue and epithelium, and contains  blood and lymph capillaries along with __________ arteries that

provide blood to the heart.  It is the same as the _________ pericardium.

 

The middle layer, called __________, consists of cardiac muscle and is the thickest layer of the heart wall.

 

The inner __________ is smooth and is made up of connective tissue and epithelium, and is

continuous with the endothelium of major vessels joining the heart.

 

Heart chambers:

The heart has four internal chambers: two upper chambers and two lower chambers.  A __________ divides the

chambers on the left side from those on the right.

Upper chambers, ___________,  receive blood returning to the heart, and have thin walls and ear-like auricles

projecting from their exterior.

Below them, the thick-muscled ___________ pump blood to the body and lungs.

 

Heart valves:

The right atrioventricular (AV) valve, called __________ valve, and left AV valve, called either ____________ or

the __________ valve, have cusps to which strings called ________ ________ attach.  These strings are, in turn,

attached to ___________ muscles in the inner heart wall, which contract during ventricular contraction to prevent

the backflow of blood through the AV valves.

 

Where are the semilunar valves found?  _________________________________________________________

What is their function?  ______________________________________________________________________

Skeleton of the Heart:

Rings of dense connective tissue surround the pulmonary trunk and aorta to provide attachments for the heart

___________ and _________ _fibers_.  These tough rings prevent dilating of tissue in this area.

 

Path of Blood Through the Heart:

Superior and inferior vena cava, __right atrium__, __tricuspid____, __right   ventricle_,

___pulmonary____, _pulmonary trunk, pulmonary arteries, pulmonary capillaries  of lungs, _

pulmonary veins_, _left atrium__, _bicuspid / mitral_ valve, _left    ventricle___, __aortic  valve, and through the

arteries to provide blood to the body cells.

 

Which part of the pathway is pulmonary?  _____________________________________________________

Which part of the pathway is systemic?  _______________________________________________________

________________________________________________________________________________________

 

What is the function of pulmonary circulation?  _________________________________________________

Of systemic circulation?  ___________________________________________________________________

Blood Supply to the Heart:

The first branches off of the aorta, which carry oxygen-rich blood, are the right and left _________

arteries that feed the heart muscle itself.  Branches of these arteries feed many capillaries of the myocardium.

 

The heart muscle requires a continuous supply of oxygen-rich blood, so smaller branches of arteries often have

_________ as alternate pathways for blood, should one pathway become blocked.

 

___________ veins drain blood from the heart muscle, and carry it to the coronary   _________, which drains into the right atrium.

Heart Actions:
    Cardiac cycle:

The cardiac cycle consists of the atria beating in unison, called atrial _________, while the ventricles rest, called

ventricular _________.  This is followed by the contraction of both ventricles, called ventricular _________, while

the atria relax, called atrial _________.  Then the entire heart relaxes for a brief moment.

 

During the cardiac cycle, pressure within the heart chambers rises and falls.  These pressure changes open and

close _________.

 

When the atria fill, pressure in the atria is ______________ than that of the ventricles, which forces the

_________ and _________ valves open.

Pressure inside atria rises further as they contract, forcing the remaining blood into the ventricles.

When the ventricles contract, pressure inside them ______________ sharply, causing the ___________ and

________ valves to close, and the ___________ and ___________ valves to open.

 

As the ventricles contract, __________ muscles contract, pulling on _________________ and preventing

the backflow of blood through the tricuspid and mitral valves.

      Heart sounds:

Heart sounds can be described as a “lubb-dupp” sound.  The first sound (lubb) occurs as the ___________

contract and the ___________ and _________valves are closing.  The second sound (dupp) occurs as

__________ relax and aortic and __________ valves are closing.

 

    Cardiac Conduction System:

A mass of merging fibers that act as a unit is called a functional __________; one exists in the atria

and one in the ventricles.

 

Specialized cardiac muscle tissue conducts impulses throughout the myocardium and comprises the cardiac

conduction system.  A self-exciting mass of specialized cardiac muscle called the _________ node (_________ node),

located in the posterior right atrium, generates the impulses for heartbeats.  Therefore, it is also called the

_________ of the heart.

 

Impulses spread next to the atrial ______________; it contracts, and impulses travel to the junctional fibers

leading to the __________ node (_________ node) located in the septum.

 

Junctional fibers are small, allowing the atria to contract before the impulse spreads rapidly over the ventricles.

The impulse proceeds to the next conduction structure, the ___________ bundle (Bundle of _His_),  which splits into

the left and right _________ _________.  These branches give rise to __________ fibers, which lead into the

ventricular myocardium and the papillary muscles.

 

    Electrocardiogram (ECG):

 

The first wave, the _________ wave, corresponds to the __________ of the atria.

The __________ complex corresponds to the ___________ of the ventricles and hides the ___________

of the atria.

The ___________ wave ends the ECG pattern and corresponds to ventricular ___________.

In each case, depolarization leads to contraction of the chamber, and repolarization leads to relaxation.

 

    Regulation of the Cardiac Cycle:

 

The amount of blood pumped at any time must adjust to the current needs of the body (more is needed during

strenuous exercise).  The SA node is innervated by branches of the _____________ and ___________

divisions of the nervous system, so the CNS helps to control heart rate. Impulses from the former speed up and

impulses from the latter  slow down heart rate.

 

The ___________ control center of the __________   ___________ maintains a balance between the

two autonomic divisions of the nervous system in response to messages from ____________, which detect

changes in blood pressure.

 

Impulses from the _________ or _________ may also influence the cardiac control center.  Body

temperature and the concentrations of certain ___________ also influence heart rate.

 

Blood vessels:

 

The blood vessels (arteries, arterioles, capillaries, venules, and veins) form a closed tubular system that carries

blood away from the heart, to the cells, and back again.

 

  Arteries:

 

Arteries are strong, elastic vessels adapted for carrying high-pressure blood away from the heart.

Arteries become smaller as they divide and become ___________.

The wall of an artery consists of an inner endothelial layer, called the tunica _______.  The middle layer, called the

tunica ___________  is made up of smooth muscle and elastic connective tissue.  The tunica __________ is the

outermost layer of connective tissue.

 

Arteries are capable of ___________ as directed by sympathetic impulses; when impulses are

inhibited, the diameter of the vessel increases, which is called _________.

 

  Capillaries:

 

Capillaries are the smallest vessels, consisting only of a layer of _________, through which substances

are exchanged with tissue cells.

Areas with a great deal of metabolic activity (leg muscles, for example) have higher densities of capillaries.

__________ sphincters can regulate the amount of blood entering a capillary bed, and are controlled

by the ___________ concentration in the area.  If blood is needed elsewhere in the body, the capillary beds in

less important areas are shut down.

 

    Capillary Exchanges:

 

Blood entering capillaries contains high concentrations of __________ and _________ that diffuse out of the

capillary wall and into the _________ ___________.

 

Why do plasma proteins remain in the blood?  ___________________________________________

____________ pressure drives the passage of fluids and small molecules out of the capillary at this point.

At the venular end of the capillary, ___________ pressure , due to the proteins in the blood, causes much of the

tissue fluid to return to the bloodstream.  ____________ capillaries collect excess tissue fluid and return it to the

circulation.

 

    Veins:

 

Small vessels called ___________ lead from capillaries, and merge to form larger ___________ that

return blood to the heart.

 

Veins have the same three layers as arteries, and have flap-like __________ inside to prevent backflow of

blood.

 

How do veins differ from arteries?  _____________________________________________________

Blood pressure:

 

Blood pressure is the force of blood against the inner walls of blood vessels anywhere in the cardiovascular

system, although the term “blood pressure” usually refers to ___________ pressure.

 

Arterial blood pressure rises and falls, following a pattern established by the cardiac cycle.  During ventricular

contraction, arterial pressure is at its __________ or _________ pressure.  When the ventricles are relaxing,

arterial pressure is at its ___________  or ___________ pressure.

 

The surge of blood that occurs with ventricular contraction can be felt at certain points in the body as a

__________.

 

Factors that Affect Blood Pressure:

 

What are the four factors that affect blood pressure?  _____________________________________________ ______________________________________________________________________________________________

 

    Control of blood pressure:

 

Blood pressure  is partially determined by ____________ output and ___________resistance.

Cardiac output is the product of ____________ volume and _______ rate, and a number of factors can affect these

variables.  Describe the factors that affect these variables:  ___________________________________ __ ___________________________________________________________________

 

The __________center of the __________ _________ in the brain stem can adjust sympathetic

impulses to ___________ in arteriole walls, adjusting blood pressure.

 

      Mechanisms of Blood Return:

 

Blood pressure at the venular end of a capillary is almost 0.  So other factors help return the blood to the heart.

 

Contractions of ___________ muscles squeeze blood back up veins one valve at a time.

 

Differences in ___________ and ___________ pressures, derived from the breathing process, draw blood back

up the veins.

 

Paths of Circulation:

      

Blood vessels can be divided into 2 major pathways, the _________ circuit, which goes from

the heart to the lungs and back, and the _________ circuit, which goes from the heart to the body cells and back.

 

Arterial System:

The ____________ is the body’s largest artery.  Be able to recognize and locate the following arteries:

 

·     Principal branches of the aorta

·     The branches of the ascending aorta are the right and left _________ arteries that lead to heart muscle.

·     Principal branches of the aortic arch include the _________, left common carotid, and left _________ arteries.

·     The descending (thoracic) aorta gives rise to many small arteries to the thoracic wall and thoracic viscera.

·     The abdominal aorta gives off the following branches: celiac, superior mesenteric, suprarenal, renal, gonadal, inferior mesenteric, and common iliac arteries.

 

    Arteries to the Head, Neck, and Brain:

·     Arteries to the head, neck, and brain include branches of the subclavian and common _________ arteries.

·     The _________ arteries supply the vertebrae and their associated ligaments and muscles.

·     In the cranial cavity, the vertebral arteries unite to form a _________ artery that ends as two posterior cerebral arteries.

·     The posterior cerebral arteries help form the circle of _________ that provides alternate pathways through which blood can reach the brain.

·     The right and left common carotid arteries diverge into the external carotid and internal carotid arteries.

·     Near the base of the internal carotid arteries are the carotid _________, which contain baroreceptors to monitor blood pressure.

 

      Arteries to the Shoulder and Upper Limb:

·     The subclavian artery continues into the armpit area, where it becomes the _________ artery.

·     In the shoulder region, the axillary artery becomes the _________ artery that, in turn, gives rise to the ulnar and radial arteries.

 

  Arteries to the Thoracic and Abdominal Walls:

·     Branches of the thoracic aorta and subclavian artery supply the thoracic wall with blood.

·     Branches of the abdominal aorta, as well as other arteries, supply the abdominal wall with blood.

 

  Arteries to the Pelvis and Lower Limb:

·     At the pelvic brim, the abdominal aorta divides to form the _________ _________ arteries that supply the pelvic organs, gluteal area, and lower limbs.

·     The common iliac arteries divide into _________ and _________ iliac arteries.

·     Internal iliac arteries supply blood to pelvic muscles and visceral structures.

·     External iliac arteries lead into the legs, where they become the _________, popliteal, anterior tibial and posterior tibial arteries.

 

Venous System:

 

Veins return blood to the heart after the exchange of substances has occurred in the tissues.     Larger

veins parallel the courses of arteries and are named accordingly; smaller veins take irregular pathways and are

unnamed.

Veins from the head and upper torso drain into the ________ _______ ________.

Veins from the legs and lower trunk drain into the _________ _______ _________.  Both drain into the _________ atrium.

 

Be able to recognize and locate these veins:

 

    Veins from the Head, Neck, and Brain:

·     The _________ veins drain the head and unite with the subclavian veins to form the brachiocephalic veins.

 

    Veins from the Upper Limb and Shoulder:

·     The upper limb is drained by superficial and deep veins.

·     The basilic and cephalic veins are major superficial veins.

·     The major deep veins include the radial, ulnar, brachial, and axillary veins.

 

    Veins from the Abdominal and Thoracic Walls:

·     Tributaries of the brachiocephalic and azygos veins drain the abdominal and thoracic walls.

 

    Veins from the Abdominal Viscera:

·     Blood draining from the intestines enters the _________ _________ system and flows to the liver first rather than into the general circulation.

·     Hepatic veins drain the liver, gastric veins drain the stomach, superior mesenteric veins lead from the small intestine and colon, the splenic vein leaves the spleen and _________, and the inferior _________ vein carries blood from the lower intestinal area.

 

 

    Veins from the Lower Limb and Pelvis:

·     Deep and superficial veins drain the leg and pelvis.

·     The deep veins include the anterior and posterior tibial veins, which unite into the _________ vein and then the femoral vein; superficial veins include the small and great _________ veins.

·     These veins all merge to empty into the common iliac veins, which then merge to form the _________ _________ _________.

 

 

 

 

Using what you know about osmosis, explain how drinking too much water can lead to the deadly condition known as hypernatremia. What effect does this have on the body cells?

Diffusion and Osmosis Worksheet

Part 1- Cell Transport Structures

         Follow this link (https://pbslm-contrib.s3.amazonaws.com/WGBH/conv19/tdc02-int-membraneweb/index.html) to the interactive cell at PBS.com. Click on the different structures and molecules to find out more about them. Use the descriptions to fill out the tables below. An example has been done for you for each table.

 

Cell Structure Describe the Function
Lipid Bilayer The main component of the plasma membrane, it allows some molecules to pass through easily and not others.
   

 

   

 

   

 

   

 

   

 

   

 

 

Move Substance How does it cross the membrane? (through the membrane/through a protein/ exocytosis) Is it being transported through Active or Passive transport?
Oxygen

 

Through the membrane Passive
 

 

   
 

 

   
 

 

   
 

 

   
 

 

   
 

 

   

 

Part 2 – Reflection: Can you drink too much water?

       Read the article titled “Can you drink too much water?” that is attached to this assignment in D2L. In the space below, answer the following reflection prompts in a paragraph.

  • Using what you know about osmosis, explain how drinking too much water can lead to the deadly condition known as hypernatremia. What effect does this have on the body cells?
  • When survivors are lost at sea, they are told not to drink the ocean salt water. Using what you know about osmosis, explain why drinking too much salt water can also be deadly. What effect would this have on the body cells?

 

 

 

Select two different seeds that are available on the counter and dissect them in half lengthwise. Observe each one under the dissecting microscope and draw and label the following structures: embryo, food, and the seed coat. (

DISCUSSION ESSAY

Select two different seeds that are available on the counter and dissect them in half lengthwise. Observe each one under the dissecting microscope and draw and label the following structures: embryo, food, and the seed coat. (Hint:refer to pg. 148)

Seed name: Soil Seed name: bestial Total magnification 10 Total magnification (0 C. Gymnosperms Observe the gymnosperms on display and read the intimillation provided to answer the following questions: What are the common names of the gymnosperm specimens on display? Are the plants you observe the saprophyte or saprophyte? Are they bearing cones? Ifs°, where are they located? What does the male cone produce? What does the female cone produce? How does the sperms (inside the pollen grain) reach the egg? Describe the shape of pine leaves. What is the benefit of this leaf shape?

In the space provided, draw and label the male and female cones on display.

159

Alonocot Distal What does the xylem transport? is the xylem a living tissue? What does the phloem transport? Es’ the phloem a living tissue? What tissue make up the wood? What tissue makes up the bark?

VASCULAR TISSUES

The xylem and phloem that makc up theyascular tissues arc present in seedless vascular plants, as well as in gymnosperms and angiospemu.

Observe a sagittal section of a stcm of a gymnosperm and an angiosperm. Recognize the xylem and phloem cells. Use the information provided next to the specimen and lathe resource binder to answer the following question:

List the features that you were able to identifr as part of the xylem and phloem.

Observe a cross section of a stem of a dicot and a monocot plant. Identify the vascular bundles that contains the xylem and phloem. Draw the arrangements of these vascular bundles for each plant (Use the 4X objective lens). Label the structures observed.

Alonocot Distal What does the xylem transport? is the xylem a living tissue? What does the phloem transport? Es’ the phloem a living tissue? What tissue make up the wood? What tissue makes up the bark?

SEEDS

Gymnosperms were the first group of plants to produce seeds, an important novelty trait in the evolution of plants that help them to become successfid and a dominant group by the time of the dinosaurs.

158

 

Discuss potential biotech applications connected with public health measurements that will help to improve the prevention of cerebrovascular accidents.

Biotech applications

Cerebrovascular insufficiency refers to a number of rare conditions that result in the obstruction of one or more arteries that supply blood to the brain. The obstruction leads to strokes or transient ischemic attacks (TIAs or “mini strokes”). The prevention of cerebrovascular accidents plays a significant role in the clinical outcome.

Question for discussion: Discuss potential biotech applications connected with public health measurements that will help to improve the prevention of cerebrovascular accidents. Provide specific examples. ( must be not more than 300 words)

How many electrons does O have? How many electron shells does Si have? How many electron shells does Na have?

Periodic Table

  1. How many protons does H have?
  2. How many protons does He have?
  3. How many protons does N have?
  4. How many protons does C have?
  5. How many protons does O have?
  6. How many neutrons does H have?
  7. How many neutrons does He have?
  8. How many neutrons does N have?
  9. How many neutrons does C have?
  10. How many neutrons does O have?
  11. How many electrons does H have?
  12. How many electrons does He have?
  13. How many electrons does N have?
  14. How many electrons does C have?
  15. How many electrons does O have?
  16. How many electron shells does Si have?
  17. How many electron shells does Na have?
  18. How many electron shells does C have?
  19. How many electron shells does He have?
  20. How many electron shells does H have?
  21. What is the atomic number of C?
  22. What is the atomic number of H?
  23. What is the atomic number of O?
  24. What is the atomic number of N?
  25. What is the mass number of C?
  26. What is the mass number of H?
  27. What is the mass number of O?
  28. What is the mass number of N?
  29. How many electrons does H have in its outer shell?
  30. How many electrons does He have in its outer shell?
  31. How many electrons does N have in its outer shell?
  32. How many electrons does O have in its outer shell?
  33. How many electrons does Si have in its outer shell?
  34. How many electrons does C have in its outer shell?
  35. How many electrons does Ne have in its outer shell?

 

When the trp repressor is bound to tryptophan, the protein can readily recognize and bind to the operator sequence. Why would this action prevent the expression of the trp operon? How would a drop in the cytoplasmic levels of tryptophan allow for the expression of the trp operon?

DISCUSSION QUESTIONS

Answer the following questions

You may provide your answers in a separate file or within this worksheet (save as a .pdf file) but for the latter, remember to TYPE YOUR ANSWERS IN RED (or another color of your choice)!

 

Part I:  Gene Regulation of the trp Operon

The following questions are about the prokaryotic trp operon (outlined below), specifically addressing how the operon is regulated in response to nutritionally poor environments.  Briefly, the trp operon includes a group of 5 genes (described below as genes A-E) that encode for the biosynthetic enzymes required to synthesize the amino acid, tryptophan.  The structure of the trp operon is shown, including the promoter sequence which contains a regulatory sequence known as an operator.  Use your knowledge of gene expression and consider the consequence for a bacterium in the following situations.

 

(4 points) The trp operon is expressed (i.e. turned ”on”) when cytoplasmic tryptophan levels are low, which allows the bacterium to synthesize tryptophan.  However, the trp operon is repressed (i.e. turned “off”) when tryptophan levels are high.  The cause of the repression is a bacterial protein known as the trp repressor.

When the trp repressor is bound to tryptophan, the protein can readily recognize and bind to the operator sequence. Why would this action prevent the expression of the trp operon?

How would a drop in the cytoplasmic levels of tryptophan allow for the expression of the trp operon? Hint:  you will need to consider your answer to Q1A.

 

(3 points) Given what you know about gene expression, consider how much “effort” the cell puts into expressing a gene product.  How would the energy requirements necessary to synthesize a protein help explain why organisms would go through the effort of regulating gene expression?  In other words, why wouldn’t a bacterium express the trp operon all the time (as opposed to only expressing it when tryptophan levels are low)?

 

(3 points) What would happen if there was a mutation that caused the trp repressor protein to bind more tightly to tryptophan (even if tryptophan levels were low)?

 

(3 points) What would happen if there was a mutation in the trp repressor binding sequence (the operator sequence) that made the repressor unable to bind (even if tryptophan levels were high)?

 

(3 points) What would happen to the cell (when tryptophan levels are low) and there was a nonsense mutation early in the coding sequence of gene D?

 

(4 points) What would happen if a mutation were introduced in th domain of the Trp repressor that changed an asparagine residue to a glycine residue?  Would this be more problematic for the cell when tryptophan levels were high or low?

(2 points) Do eukaryotes have operons?  If not, explain how eukaryotes would regulate the expression of multiple related genes so that they are expressed at the same time.

 

Part II:  Gene Regulation of the ara Operon

In the absence of glucose, Escherichia coli can still generate the energy necessary for proliferation by using the pentose sugar arabinose.  The figure below outlines the arabinose (ara) operon, which encodes for all the proteins necessary to achieve this switch in sugar metabolism.  The araA, araB and araD genes encode the enzymes for the metabolism of arabinose while the araC gene encodes a transcription regulator that binds adjacent to the promoter of the arabinose operon.  To understand the regulatory properties of the AraC protein, you engineer a mutant E. coli in which the araC gene has been deleted so that you can look at how the presence or absence of the AraC protein affects the expression of the AraA enzyme.

 

  1. (4 points) If the AraC protein works as a repressor, would you expect araA RNA levels to be high or low in the presence of arabinose in the araC– mutant cells?  What about in the absence of arabinose?  Explain your answer.Your findings from the experiment are summarized in the following table.

(4 points) Do the results indicate that the AraC protein regulates arabinose metabolism by acting as a repressor or an activator?  Explain your answer

BONUS (1 point):  Below is a picture of a transcription factor whose asparagine side chain (shown on the right) is contacting an adenine ring in a DNA molecule.

Which of the amino acids shown below would be able to make the same H-bonding contacts as the Asparagine? Circle your answer.

Would the substitution of the amino acid from part A change the strength of the protein-DNA complex? Why or why not?

 

 

 

 

 

 

 

What do you consider the best argument of “A Modest Proposal” and why? Support your answer.

ASSIGNMENT

A Modest Proposal” is a satire and you should read it with this in mind. Swift is creating an overblown and preposterous solution to a societal ill in order to call attention to how dire the situation really is (in essence saying the poverty is so bad that if we don’t get it under control, we could start to think this a valid solution). Satire was a very popular mode at the time and Swift’s readers would have understood that he was writing in this mode. What do you consider the best argument of “A Modest Proposal” and why? Support your answer.

 

Research the social impact of a problem of interest and make your case why your team should work on it. Challenge should be focused and actionable.

Problem of interest

Research the social impact of a problem of interest and make your case why your team should work on it. Challenge should be focused and actionable. Consider translating your challenge but don’t get into biological models or solution ideas.

  • Word count: text body must be 500-750 words (no more, no less). This is short (1.5 pages). Calibri or Arial, 12 pt font, 1 inch margins.
  • Give your proposal a short title.
  • Include a bibliography of your sources (primary literature please, not websites). Bibliography does not count towards the word count.