Understand minimally invasive surgeries (MIS) and conventional surgeries involved in degenerative mitral diseases by referring to Minimally Invasive Surgical Mitral Valve Repair: State of the Art Review.

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Instructions

  • Understand minimally invasive surgeries (MIS) and conventional surgeries involved in degenerative mitral diseases by referring to the following:
  • A meta-analysis of minimally invasive versus conventional mitral valve repair for patients with degenerative mitral disease by Christopher Cao and the 29 references used for that article.
  • Minimally Invasive Surgical Mitral Valve Repair: State of the Art Review

 

Those can be found in this google drive link:

https://drive.google.com/open?id=1beCUWMH3r0q7UYXSv_zrr2sqbOZ1mL0S

  • Write an introduction (around 1000 – 1200 words) of minimally invasive versus conventional surgeries for degenerative mitral valve diseases consisting of the following contents:
  • History of minimally invasive surgeries and conventional surgeries for degenerative mitral valve diseases (200 – 250 words)
  • Draw timeline to illustrate the history.
  • Refer to background reference word document for some information on history if necessary.
  • Degenerative mitral valve diseases (200 – 250 words)
  • Images on: healthy mitral valve VS degenerative mitral valves comparison
  • Minimally invasive surgeries (MIS) for degenerative mitral valve diseases (400 words)
  • Types of MIS for degenerative mitral valve diseases
  • Place some emphasize on femoral-femoral bypass – as I am conducting this MIS on my patients.
  • 2 images of MIS degenerative mitral valve diseases e.g. image of ministernotomy
  • Conventional surgeries for degenerative mitral valve diseases (300 words)
  • Types of conventional surgeries for degenerative mitral valve diseases.
  • 2 images of conventional surgeries for degenerative mitral valve diseases e.g. image of sternotomy.
  • Present data on:
  • Prevalence of MIS and conventional surgery for mitral valve disease.
  • Proportion of both MIS and conventional surgery for mitral valve disease at the moment.
  • Relevance of MIS and conventional surgeries.
  • References – 30 references (*can consider references in google drive link above, but it is recommended to use other references that are newer and better as some references in google drive link are old i.e. in 1990s), preferably year 2000 – 2019, Harvard referencing.

Critically review the production of biotechnological products in transgenic organisms. Mainly focus on the molecular genetics aspects which are involved in the production of a biotechnological product.

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Coursework MOLE1006.
2000 words (except references)

Critically review the production of biotechnological products in transgenic organisms. Mainly focus on the molecular genetics aspects which are involved in the production of a biotechnological product.

Critically review the above topics using at least THREE recently (last 5 years) published key journal papers. Review 3 papers to compare either THREE gene constructs in one transgenic species OR compare ONE specific gene constructs in THREE species. Indicate which the three papers are: you will be expected to have a detailed understanding of these 3 papers but we will not expect you to be as familiar with other papers you may wish to cite.

 

How will you control the other first respondents or law enforcement officers? What challenges do they pose to a forensic investigator? Explain.

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FORENSIC BIOLOGY
2nd ed.
RICHARD LI
Carl and Joseph were in the woods of Georgia in early fall. They had set up a camp because they were both deer hunters. In the fall of years when the weather is cooler, deer are very prevalent. On this cool November morning, the men were walking through the woods in their quest for deer. On the second day of being in the woods, walking through what was really thick brush and uneven terrain, one of the men slipped and fell into what appeared to be a covering of a hole in the ground. As he began to try and pull himself out, he saw several skulls and bones lying around. He immediately screamed for his friend, who assisted him in getting out of the hole. Together, they looked in and saw skeletons and what appeared to be a decomposing body.

The two men called the local police. The police arrived, secured the area, and called for the forensic team to come and investigate. You are the forensic person that has been asked to identify the 5 skeletons in the grave and the body that was only partially decomposed.

Assignment Guidelines;

Address the following in 10–12 pages:
Why will this particular case require the use of forensic biology? Explain in detail.
When you arrive on the scene, what is your first course of action? Describe your process, and be specific.
How will you avoid contamination at this stage of the investigation? Explain.
How will you control the other first respondents or law enforcement officers? What challenges do they pose to a forensic investigator? Explain.
What will you do to identify the remains at this crime scene? Explain.
What is the documentation process for collecting and preserving this type of evidence? Explain.
How will you transport your evidence to the lab safely? Explain.
Once you arrive back at the lab, what significant risks of contamination exist? Explain.
How will you avoid this contamination? Explain.
What is the process for DNA analysis on the decomposing body?
What specific tests will you use? Explain.
How will serology play a role in the selected testing processes? Explain.
Using this decomposing body as an example, what is the process that you will follow to properly conduct this DNA test?
What challenges or barriers exist when you begin to interpret the results of your DNA test? Explain in detail.
How large of a role will facial reconstruction play in this investigation? Explain.
Next, provide 2 scenarios of court case outcomes regarding this investigation.
One scenario must result in the successful identification and conviction of the perpetrator. You will need to fill in the blanks with regard to physical evidence and other necessary details.
The other scenario must result in a wrongful conviction. You will need to identify the elements that lead to this wrongful conviction.
Be sure to reference all sources using APA style.

Provide 2 significantly different examples where forensic biology should NOT be applied to a criminal investigation. Justify your examples.

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Assignment Details(minimum 300 words)

Address the following in your main post:
In your opinion, when should forensic biology be applied to criminal investigations? Explain.
Provide 2 significantly different examples where forensic biology should be applied to a criminal investigation. Justify your examples.
Provide 2 significantly different examples where forensic biology should NOT be applied to a criminal investigation. Justify your examples.
Should the cost of forensic biology tests and activities be considered when conducting a criminal investigation? Why or why not? Explain.
How do you think the field of forensic biology can be improved with regard to criminal investigations? Explain.

Briefly summarize the controversial issue Kim Andersen discovers about the sponsors of industries such as the American Heart Association, the American Cancer Society, the Susan G. Komen Foundation, and the American Diabetes Association. 

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Assignment 2

I would like you to watch the documentary titled, “What The Health” and answer the following questions. You can watch the full documentary either on Netflix or Youtube. 

  1. The beginning of the film brings up some findings from the World Health Organization that links processed meat to an increase in cancer. According o these findings, just one serving of deli meats daily can increase a person’s risk of colorectal cancer by?
  2. The World Health Organization classifies processed meat as a Group 1 Carcinogen, the same group as?… asbestos, and plutonium.
  3. When, the filmmaker (Kim Andersen) calls the American Heart Association, what question is he trying to get answered?
  4. Briefly summarize the controversial issue Kim Andersen discovers about the sponsors of industries such as the American Heart Association, the American Cancer Society, the Susan G. Komen Foundation, and the American Diabetes Association.
  5. Please share any other thoughts you had while watching the film.

 

Reducing maternal mortality due to sepsis in Uganda: What would you propose to do with this money? A detailed justification of your spending is required.

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PBL 1: Reducing maternal mortality due to sepsis in Uganda.

Despite significant investment, much from oversees Aid, maternal mortality rates in Uganda have barely declined in recent years and remain amongst the highest in the world. This failure is particularly frustrating given that a WHO blueprint for reducing maternal morbidity and mortality based on provision of skilled birth attendants and better management of obstetric emergencies, in particular sepsis, is well established. Research focused on improving provision of these resources is likely to have a significant impact, and thus the UK’s National Institute for Health Research is offering up to £5 million over 4 years to support research initiatives in this area. What would you propose to do with this money? A detailed justification of your spending is required.

Write about:

  • What preventive methods can be taken?
  • Sensible diagnostic approaches in Uganda

250 – 300 words max, 10 references Harvard APA (*use sources from 2013 – 2020)

How significant is DNA evidence in determining the outcome of modern court cases? Explain in detail.

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U.S. REFERENCES, NO TITLE PAGE PLEASE. Include FORENSIC BIOLOGY.

Assignment Details;
DNA profiling is used in other kinds of court cases besides just criminal cases. Other cases in which DNA profiling is used are custody, paternity, estate settlement, hair analysis, forensic IT, and many more. Because of the information contained in a single sample, it is very important that the same be obtained and maintained in a manner that does not jeopardize the DNA sample.
Address the following in your main post:
List and discuss the different processes that should be utilized to avoid contamination of DNA samples.
What do you think is the most significant contamination issue with regard to DNA testing? Explain.
Provide 2 examples where court decisions have been made directly because of DNA evidence contamination.
How do you feel about the outcomes of these cases? Explain.
How significant is DNA evidence in determining the outcome of modern court cases? Explain in detail.

Create a concept map of the various components from your table, using arrows to show the pertinent connections between them.

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Course: Applied Pathophysiology II

Title of Assignment: Written Table and Concept Map – 15 points

Curricular concept: Evidence-Based Care and Quality Improvement

Macro concept: Physiological Integrity

Micro concepts: Metabolism, Neuro-cognition, Infection, Regulatory, Oxygenation, & Perfusion

Exemplars: Gestational Diabetes, Hydrocephalus, Meningitis, Nephrotic syndrome (Toddler),                                  Acute Pancreatitis, Pleural Effusion, Sickle cell crisis

Purpose: Explore pathophysiologic processes that occur in diseases and connect them to clinical manifestations, potential complications, and clinical management including the nurse’s role.

Objectives:

  1. Describe the normal structure and function of cell, tissue, organ, and body systems for acute disease processes.
  2. Correlate normal body functioning to physiologic changes that occur as a result of disease processes.
  3. Apply the science of pathophysiology to common acute system disorders across the lifespan.
  4. Correlate normal body functioning to physiologic changes that occur as a result of disease processes.

Suggested Resources for Concept Map: Cacoo.com, Microsoft Powerpoint, Microsoft Visio or other system for developing your concept map.

Directions:

  1. Research delirium using current texts and scientific journals. One source must be quantitative or qualitative research related to your exemplar.
  2. Complete a table (example on following page). Include the following components: (see rubric for more details)
    1. Definition of the exemplar and the related epidemiology to include holistic, environmental, stress, or genetic related maladaptations of the system involved.
    2. Explanation of the pathophysiology of the exemplar to include changes in structure and function.
    3. Description of the clinical manifestations in relation to the pathophysiology and assessments to include identification of the diagnostic tests for the exemplar.
    4. Description of the potential complications of the exemplar.
    5. Explanation of the clinical management including current therapies and the effect on the pathophysiology of the exemplar.
    6. Discuss the nurse’s role and implications on nursing practice regarding management of the exemplar.
    7. Discuss the ethical implication of using human subjects in research and describe the importance of maintaining accuracy of data collection in research on the population impacted by your exemplar.
    8. References are comprehensive, relevant, and current (within the past 5 years). At least 2 of the references are from peer-reviewed articles that were published within the last five years. One reference must be related to research on the exemplar. For most topics, nursing literature alone will not provide sufficient depth. Sources from medicine and other sciences are encouraged. Be sure to site in text all information you take from a source.
    9. Follow APA format for your reference page.
  3. Create a concept map of the various components from your table, using arrows to show the pertinent connections between them.
  4. One team member will turn in your group’s work to the drop box in D2L by the designated due date. Each team member will turn in a peer review form to the drop box in D2L by the designated due date.

Example of Table and Concept Map                                    

This is an example of a table for the assignment. You can design one of your own, but be sure all required components are covered in the table.

Definition of ‘Exemplar’
Pathophysiology
Clinical Manifestations
Diagnostic Testing
Clinical Management
Nurse’s Role
Ethical Research Implications

Concept Map- This map does not contain all required component of the assignment but is an example of how to show connections in a concept map.

Identify discrepancies between identified practice standards and current practice that may adversely impact patient outcomes. 

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Root Cause Analysis Scholarly Writing Paper

Purpose: The nurse participates in establishing, maintaining, and improving the healthcare environment, through utilization of a Root Cause Analysis to correct a clinical health problem.

Objectives: 

  1. 1. Utilize the root cause process to identify a health care problem within the organizational structure.
  2. Determine the relationship between different root causes for a problem.
  3. Discuss improvement methods to promote quality, safety and social justice while reviewing a root cause scenario
  4. Identify discrepancies between identified practice standards and current practice that may adversely impact patient outcomes.

Required Reading:  

Optional Resources:

Directions:

  1. From the perspective of the Risk Manager, describe your specific health care event. What happened, who was involved?
  2. Collect Data from your peers in your color group to help determine the root cause of the problem.
    1. What is the sequence of events? Use the RCA Sequence of Events tool. Complete these factual events in order to help make sense of the story leading up to, during and after the event. Include times as much as possible. Do not include opinions or interpretation of the events.
    2. Categorize possible causes and develop a Fish Bone Diagram (Ishikawa) including a minimum of one cause in each of the 6 fish bones on the diagram. Include all probable causes as appropriate.
    3. Individually, categorize possible causes for the problem/event. Fill out three 5 Why’s forms– Start with the problem on each form and then drill down on three separate forms of this tool to obtain three possible causes. (These 5 forms are part of the Appendix and will be turned in at the first due date for faculty feedback. See Step 11 prior to submission.)
  3. In the body of the paper, explain the sequence of events/data collection. Describe your thought process while categorizing all possible causes on the Ishikawa Diagram. Focus on the 3 most probable causes for the problem. Refer to the Ishikawa diagram and your 5-Why’s. Why did they happen? Identify which conditions allowed the problem to occur.
  4. Next, identify one of the three probable causes as the primary root cause and explain why you believe this is the primary root of the problem. Discuss how various roots could interplay to cause the problem.
  5. Identify a national benchmark or standard of care that should be met in this scenario as it relates to the primary root cause.
  6. Identify your expected outcome (SMART) that would help this color group meet the national benchmark or standard of care.
  7. Cite your credible source to support the benchmark or standard of care and the goal/outcome.
  8. Intervention – What should be done to prevent the problem from recurring? Formalize your realistic plans for implementing change that looks directly at the primary root cause you identified. Also discuss barriers to implementation.
    1. How will you implement this change?
    2. Include an expected timeline.
    3. What are the risks and/or barriers of implementing the change?
  9. Evaluation – When would be a good time to evaluate whether or not your changes had the desired effect? Did your interventions achieve the desired outcome?
    1. What criteria will you measure so you know the Outcome was achieved?
    2. Who (title of person) is responsible for the final Outcome?
  10. The conclusion should not have any new data presented.
    1. Summarize the problem, the missed benchmark, and your prevention plan.
    2. How does this incident apply to your probable future nursing practice? In other words, what did you learn?
  11. References – Research a minimum of five sources (within the last 7 years); at least two must be peer reviewed health care journals.
  12. Include the Sequence of Events, three separate 5 Why’s, and the Ishikawa diagram as appendices at the end of your paper. Refer to the data presented in each within your paper. g. See Appendix B which describes the … Also remember to follow APA formatting when deciding on the correct order in which to place the forms of the appendix.
  13. Proof read your scholarly paper and compare to the rubric.