Why you would like to be considered for the UPN Summer Research Experience.
Ensure to address:
-your career goals
-reasons for wanting to engage in summer research
-how the UPN program fits into your career plan
This week you learned about carbohydrates and the importance of glycolipids, glycoproteins, and glycosylation for the functional interaction between the different components found in the extracellular matrix (ECM). You further heard about the importance of the proper sequence of the carbohydrates on glycoproteins (the “sugar code”) and the key role of sialic acid in many important cellular processes, ranging from cell-cell interaction, immune function, and cancer. You heard that the extracellular carbohydrate coat of cells, called glycocalyx, plays a role in tumor formation and metastasis. As you work on this assignment, consider that approximately half of all human proteins known to date are glycosylated and the majority of cancer biomarkers are comprised of glycoproteins. About 270,000 new cases of breast cancer are diagnosed in the U.S. per year and 6.9% of all cancer-related deaths will result from breast cancer. Also consider that the human receptor tyrosine-protein kinase erbB-2 (HER2), one of the proteins found mutated in many breast cancer patients, has multiple sites of N-glycosylation important for its biological function.
Overview:
Types of Selection
In this activity you will choose one of the three types of natural selection and create a scenario to illustrate how it affects the traits of a population. You will describe your scenario and reasoning in an essay.
Background Information:
There are three types of natural selection: directional, disruptive, and stabilizing. Each type selects for a different form of a trait within a population.
• Directional selection selects for one extreme of a specific trait. A graph representing the trait within a population would have a peak on the left or right side, but not both. • Disruptive selection selects for BOTH extremes of a specific trait. A graph representing the trait within a population would have two peaks on both the left and right side. • Stabilizing selection selects for the average of a specific trait. A graph representing the trait within a population would peak towards the middle.
Assignment:
In this assignment you will create a scenario that illustrates one of the three types of natural selection. Your scenario must include the type of organism and their population, three variations of a specific trait, and how the population shifted from one version of the trait to another and why. Additionally, you should explain your reasoning as to how this scenario models this type of selection.
Start by choosing one of the three types of selection and an organism to use in your scenario. Identify a specific trait of that organism and three variations of this trait. The variations should represent a spectrum of the trait such as small, medium, large, or light, medium, dark, or smaller amounts, medium amounts, larger amounts. Be creative in developing your scenario and describing the selection of your chosen trait.
Writing Prompt:
Write an essay describing a scenario that illustrates one of the three types of natural selection. Your essay must include the following: a description of the chosen type of selection, an organism and population, three different variations of a specific trait, and how the population shifted from one version of the trait to another and why.
Which of the following are anaerobic reactions?
The lessons we take from obstacles we encounter can be fundamental to later success. Recount a time when you faced a challenge, setback, or failure. How did it affect you, and what did you learn from the experience?
Answer these questions and respond to at least one other student. Please use complete sentences, proper grammar, and citations as needed (when seeking outside information from the lecture).
1. Discuss the proposed involvement of dopamine on ADHD. (1 paragraph minimum)
2. Select a brain region from the lecture that is proposed to be involved in ADHD. Discuss its possible role. Provide information from one additional outside source and cite accordingly (APA). (2 paragraph minimum)
3. After watching the Ted Talk on ADHD, discuss, if it did, how this shifted your viewpoint on ADHD. (1 paragraph minimum)
What one problem would you like to see solved by science, and why? It can be anything – a disease, an environmental issue, even finding life on other planets! Be specific – for example, if you pick a disease, be specific if there’s more than one form of that disease. Also, think globally (would the biggest problems in the U.S. be the same problems around the world?).
1. Futile efforts to memorize all of the EKG criteria for left ventricular hypertrophy), comes to your office for a routine checkup. She is new to your practice and has not seen a doctor since her last child was born, which was more than 20 years ago. She has no specific complaints other than an occasional headache. Routine physical examination is unremarkable, except that you find her blood pressure is 170/110 mm Hg. She is unaware of being hypertensive. You would like to know if her hypertension is long-standing or of recent onset. Your laboratory assessment includes measurement of serum electrolytes, creatinine, and blood urea nitrogen; a urinalysis; a chest x-ray; and the EKG shown below. Is the EKG helpful?
2.Tom L. is a 23-year-old marathon runner. Nearing Central Park at about the 20-mile mark of the New York Marathon, he suddenly turns pale, clutches his chest, and drops to the ground. Another runner, although on pace for a personal best, stops to help. Finding Tom pulseless and apneic, he begins cardiopulmonary resuscitation. The timely intervention proves lifesaving. Tom responds, and moments later, the following EKG is taken as he is being rushed to the nearest hospital. Why did Tom collapse?
Directions:
Grading:
Grading is based on:
Example:
Hepat/itis
wr S (LPN, 2011)
Oste/o/arthr/itis
wr cv wr s (Smith, 2012)
Cardi/o/logist
wr cv s (JAMA, 2009)
Your task is to complete the questions in the problem set. Read each question carefully and identify your given values. Show the formulas and calculations used to solve each problem.
Questions
In one year, biologists tracking a bear population counted 33 new bear cubs in a population of 546 bears.
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