Review your healthcare experience and your dream job as described in Module 1. Create a 1 – minute “elevator pitch” which explains how your RN practice will change in the next 10 years.

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PowerPoint presentation

This week’s presentation will have four parts.

Now that you have completed this course, describe what has changed in the way you think about returning to school.
Review your healthcare experience and your dream job as described in Module 1. Create a 1 – minute “elevator pitch” which explains how your RN practice will change in the next 10 years. This elevator pitch will be in an audio format. You can think about the healthcare changes learned in this course such as innovative care for aging populations, increasing numbers of individuals with chronic illness, or accreditation and standards of care.

You are already enrolled in a baccalaureate program, which will prepare you academically for the future. Throughout this course, you have also practiced clinical judgment, ethical decision making, management and delegation as an RN. Identify 3 – 4 additional experiences and skills you will need to be a nurse of the future.
Reflect on the people, attitudes, and support systems that you identified as your sources of support in Module 1. Share 2 – 3 specific instances where you used that support to be successful in this class.

Read and analyze Dr. Richards’ dissertation to answer the following questions using complete sentences. What type of quantitative research design was used? What was the population that was used for this study? What was the sample size used in the study?

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Quantitative Article Analysis

Questions:

Read and analyze Dr. Richards’ dissertation to answer the following questions using complete sentences. What type of quantitative research design was used? What was the population that was used for this study? What was the sample size used in the study? Describe the instrumentation/s that were used to collect the data. Describe what statistical analysis was conducted (descriptive, inferential and/or predictive) and name the specific tests used. What were the main findings? What was one of the limitations of the study? What recommendations for future research did the author(s) make? How can you incorporate the findings into your professional/personal practice?

Rate the readability of the article on a 5 point scale (1 = difficult; 5 = easy) Provide APA citation for above article: Qualitative Article Analysis. Read and analyze this study to answer the following questions using complete sentences. What type of qualitative research design was used? What was the sampling strategy used and size/characteristics of the study? Describe how the researchers collected the data. Describe how the researchers analyzed the data. What were the main findings? What was one of the limitations of the study? What recommendations for future research did the author(s) make? How can you incorporate the findings into your professional/personal practice? Rate the readability of the article on a 5 point scale (1 = difficult; 5 = easy) Provide APA citation for above article:

Describe a situation where you experienced a lollipop moment. Identify the leadership characteristics of the individual (s) involved in creating that moment for you. Or you can describe a situation in which you created a lollipop moment for someone else and share your leadership characteristics.

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Dudley, D. (n.d.). Everyday leadership.

Links to an external site.(6:02 minutes). This video is closed-captioned and has a transcript.

  • https://www.youtube.com/watch?v=HR2UnsOuKxo

After viewing the video, please think about lollipop moments in your healthcare work experience.

Describe a situation where you experienced a lollipop moment.
Identify the leadership characteristics of the individual (s) involved in creating that moment for you. Or you can describe a situation in which you created a lollipop moment for someone else and share your leadership characteristics.
Describe how the leadership characteristics that create lollipop moments can be applied to your professional nursing role.

Discuss the strengths and weaknesses to the business plan for your final proposal. Identify areas of strength and weakness related to financial and budgeting principles discovered through your pre- and post- self-assessments comparison.

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Week 8

REFLECTION (Refer to attachment to answer below questions)

1. Discuss the strengths and weaknesses to the business plan for your final proposal.

2. Identify areas of strength and weakness related to financial and budgeting principles discovered through your pre- and post- self-assessments comparison.

What are the differences between and patient impacts of hypothermia and hyperthermia? What education should be provided to patients and families to avoid the extreme temperature variations?

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Module 10 – Written Assignment Hypothermia and Hyperthermia Worksheet

Name:

Date:

Complete all lesson content and assigned readings. Make sure you are focusing on:

  • Differences between hypothermia and hyperthermia
  • Patient impacts from hypothermia and hyperthermia
  • Patient education for clients and families to avoid extreme temperature variations

Instructions:

  • Answer the questions listed below using complete sentences.
  • Use correct grammar, spelling and APA format.
  • Support your answers using credible sources such as textbooks, course materials, and evidence-based articles (1 Point)

Resources:

How do I know if a source is credible?

How do I find evidence-based practice articles? Or nursing best practices?

  1. What are the differences between and patient impacts of hypothermia and hyperthermia? (2 Points)
  2. What education should be provided to patients and families to avoid the extreme temperature variations? (2 Points)

Write a 2 page paper addressing the sections below of the research proposal.

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Nursing Research Identified Problems Stroke Patients and the Lack of Access to the Community Resources.

Write a 2 page paper addressing the sections below of the research proposal.

Methodology
• Extraneous Variables (and plan for how controlled).
• Instruments:

Description, validity, and reliability estimates, which have been performed (on a pre-established measure). Include plans for testing the validity and reliability of generating your own instrument(s).
• Description of the Intervention
• Data Collection Procedures

Do stroke patients lack access to community resources?

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Stroke Patients and the Lack of Access to Community Resources

Problem

The problem is identified as the lack of access to community resources by stroke patients who have difficulty navigating the community. This is because they have difficulty getting around.

Question

Do stroke patients lack access to community resources?

Sampling

The sample will be selected from a database of stroke patients admitted to the hospital (Teasell et al., 2020).

Using a non-probability convenience sample is appropriate to the design because it represents an ideal population based on the characteristics of those in need of care. This method also allows for more accurate estimates of the universe of interest, which is important because the sample size was manageable (Norrving et al., 2018). Many variables could affect results, such as age and other conditions that may affect stroke patients’ ability to return home following discharge from the hospital.

The sample does not reflect the population identified in the problem statement because several variables could have influenced results, including age and other medical conditions that may affect stroke patients’ ability to return home after discharge from the hospital (Zawawi et al., 2020).

The sample size was adequate for this study since it gave enough information for descriptive statistics to be used to analyze the data meaningfully. However, the small sample size (N=20) and limited amount of data acquired during this investigation restrict the study’s capacity to generalize its findings.

These results apply to all stroke patients who were recently discharged from hospitals (Masterson et al., 2020).

Explain the agonist-to-antagonist spectrum of action of psychopharmacologic agents, including how partial and inverse agonist functionality may impact the efficacy of psychopharmacologic treatments.

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Discussion Essay

Respond to at least two of your colleagues on two different days in one of the following ways:

  • If your colleagues’ posts influenced your understanding of these concepts, be sure to share how and why. Include additional insights you gained.
  • If you think your colleagues might have misunderstood these concepts, offer your alternative perspective and be sure to provide an explanation for them. Include resources to support your perspective.

 Joseph

Post a response to each of the following:

  1. Explain the agonist-to-antagonist spectrum of action of psychopharmacologic agents, including how partial and inverse agonist functionality may impact the efficacy of psychopharmacologic treatments.
  2. Compare and contrast the actions of g couple proteins and ion gated channels.
  3. Explain how the role of epigenetics may contribute to pharmacologic action.
  4. Explain how this information may impact the way you prescribe medications to patients. Include a specific example of a situation or case with a patient in which the psychiatric mental health nurse practitioner must be aware of the medication’s action.

 

Discussion 1 – Initial Post

Understanding a medication’s action and physiological effect is an essential skill for any prescriber to practice safely. This is especially true when prescribing psychiatric medications due to their impact on brain chemistry and function. APRNs should ensure that there is no possibility of harmful drug-drug interaction and adverse drug events when prescribing a new medication. Understanding the role of agonists and antagonist drugs is one way to reduce the risk of adverse drug events. A classic example is that the APRN would recognize that lithium would be contraindicated in a patient with a history of bipolar disorder and chronic hyponatremia due to lithium absorption increasing in the absence of sodium (Hedya et al., 2022).

Medications have two properties: affinity and intrinsic efficacy (Berg & Clarke, 2018). Affinity describes how well a drug can bind to a receptor and “is unique for each drug-receptor pair” (Berg & Clarke, 2018). Intrinsic efficacy describes the medications’ ability to affect the activity of the receptor and influence associated cell activity (Berg & Clarke, 2018). Agonist drugs possess affinity and intrinsic efficacy, while antagonist drugs have affinity but no intrinsic efficacy (Berg & Clarke, 2018).

Full agonist drugs change receptor activity to produce the maximum response, while a partial agonist can create a milder reaction (Berg & Clarke, 2018). Inverse agonists have the opposite effect of an agonist (Berg & Clarke, 2018; Nutt et al., 2016). Inverse antagonists were first observed in benzodiazepine animal studies, where certain drugs exacerbated anxiety and produced seizure activity in the animal test subjects (Nutt et al., 2016). Antagonist drugs have receptor-blocking or inhibitory effects, such as MAOIs or SSRIs, and are the most prescribed type of psychiatric drugs (Berg & Clarke, 2018; Nutt et al., 2016).

G-coupled protein receptors (GPCRs) and ion-gated channels both function as synaptic transmission sites; however, they differentiate from one another in that ion-gated channels open an ion channel and directly bind with neurotransmitters, while GPCRs signal a G-protein to indirectly bind with an ion channel (Alexander et al., 2011; Wang et al., 2018; Lakna, 2022). When GPCRs receive a chemical signal, they request either the binding to GTP to activate the channel, or GDP, to inactivate the channel (Wang et al., 2018). Ion-gated channels are located along the cell membrane and allow sodium, potassium, calcium, and chloride to pass directly through the cell membrane when signaled (Lakna, 2022).

The APRN must recognize the effect of epigenetics, or the changes to how a patient’s genes work due to environmental factors or personal behavior, and how these changes may impact the effectiveness of medication (CDC, 2022). Epigenetics most often affects messenger proteins that influence the messenger’s ability to activate or deactivate (CDC, 2022). The good news is that epigenetic changes are reversible and can be affected by changes to an individual’s environment or behavioral practices, such as changing a diet or quitting smoking (CDC, 2022).

References

Alexander, S. P. H., Mathie, A., & Peters, J. A. (2011). Ligand-gated ion channels. British Journal of Pharmacology, 164(1), 115-135. doi: https://doi.org/10.1111/j.1476-5381.2011.01649_4.xLinks to an external site.

Berg, K. A., & Clarke, W. P. (2018). Making sense of pharmacology: Inverse agonism and functional selectivity. International Journal of Neuropsychopharmacology,21(10), 962-977. doi: https://doi.org/10.1093%2Fijnp%2Fpyy071

ESSE

Post a response to each of the following:

  1. Explain the agonist-to-antagonist spectrum of action of psychopharmacologic agents, including how partial and inverse agonist functionality may impact the efficacy of psychopharmacologic treatments.
  2. Compare and contrast the actions of g couple proteins and ion gated channels.
  3. Explain how the role of epigenetics may contribute to pharmacologic action.
  4. Explain how this information may impact the way you prescribe medications to patients. Include a specific example of a situation or case with a patient in which the psychiatric mental health nurse practitioner must be aware of the medication’s action.

 

Week 2 Initial Discussion  

Hello everyone,

The chemical that binds to the receptor is called the agonist hence the agonist maybe be a psychopharmacologic agent. Affinity is described as the ability of a drug to attach to the receptor and causes a change in the host cell. Agonists also possess efficacy which is determined by the ability to start up the receptor.

On the other hand, antagonist binds to receptors (affinity) but cannot activate the receptor, hence they lack efficacy. An antagonist inhibits an agonist from binding to the receptor, preventing its ability to activate the receptor (Weir, 2020).

Understanding: How I understand this is, someone overdosed on opioids (agonists) and is then given naloxone (antagonist).

A partial agonist does not produce the full response as an agonist which means it has less efficacy. I think an example of a partial agonist would be a nicotine patch. This is a partial dose of nicotine which reduces the efficacy of the drug nicotine compared to smoking a cigarette.

An inverse agonist causes the reverse effect of an agonist when a receptor is active without an agonist.

G-coupled proteins (GPCRs) are responsible for connecting the signal between agonist binding and activation of channels. While Ion gated channels control communication between neurons (Stern et al., 2016).

Research has shown that some diseases are able to be identified early in life via epigenetics. When the disease has been identified scientists are able to develop personalized drugs (Gianfrancesco et al., 2019).

When prescribing medications to patients it is important to have a thorough history. It would also be wise to obtain labs (CBC, BMP, kidney function, liver panel, and thyroid) to identify a baseline. For example, lithium has been known to cause renal failure (Schoot et al., 2020). However, it may not be the best option for a patient with renal disease or a patient with elevated creatinine.

References  

Gianfrancesco, O., Bubb, V. J., & Quinn, J. P. (2019). Treating the “E” in “G × E”: Trauma-Informed Approaches and Psychological Therapy Interventions in Psychosis. Frontiers in Psychiatry, 10. https://doi.org/10.3389/fpsyt.2019.00009 Links to an external site.

 

Reflect on the population in your area of practice. Consider the most appropriate use for this population and potential challenges that may affect sampling in this population. Then think about how you might address these challenges and what strategies you might implement. How might a different population yield similar or conflicting results?

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Quantitative Methods

Reflect on the population in your area of practice(55-100yearold). Consider the most appropriate use for this population and potential challenges that may affect sampling in this population. Then think about how you might address these challenges and what strategies you might implement. How might a different population yield similar or conflicting results?

The student will:

  • 1)Analyze re searchable populations in area of practice.
  • 2)Evaluate selection of appropriate populations in a research study.
  • 3)Analyze challenges in obtaining data samples from research populations.
  • 4)Recommend strategies to address data collection challenges in obtaining data samples from research populations.

What principles of patient confidentiality might be an issue? Consider legal and ethical. How might this nurse use a communication device to support safe patient practices?

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Discussion Question

A nurse colleague uses his personal cell phone to take a photo of a patient’s wound and then sends a message with the photo to the primary care provider via text. Consider the following in your discussion post:

What principles of patient confidentiality might be an issue? Consider legal and ethical.

How might this nurse use a communication device to support safe patient practices?

What would your organization’s policy on ‘personal communication device use in a patient care setting’ reveal related to this case? (If your organization does not have a written policy, or you are not currently working in an organization, what do you think should be included in such a policy and why?)